<html><head><meta http-equiv="Content-Type" content="text/html charset=windows-1252"></head><body style="word-wrap: break-word; -webkit-nbsp-mode: space; -webkit-line-break: after-white-space; "><b id="docs-internal-guid-65a2c08e-589a-57a0-6964-66f0a6f81ee7"><div style="line-height: 1.2; margin-top: 0pt; margin-bottom: 0pt; "><b id="docs-internal-guid-65a2c08e-589a-57a0-6964-66f0a6f81ee7"><div style="line-height: 1.2; margin-top: 0pt; margin-bottom: 0pt; "><span style="font-size: 16px; font-family: Arial; vertical-align: baseline; white-space: pre-wrap; ">Spring 2015 Xenbase Newsletter</span></div><div style="line-height: 1.2; margin-top: 0pt; margin-bottom: 0pt; "><span style="font-size: 16px; font-family: Arial; vertical-align: baseline; white-space: pre-wrap; "><br></span></div><div style="line-height: 1.2; margin-top: 0pt; margin-bottom: 0pt; "><b id="docs-internal-guid-65a2c08e-58b2-5304-4f61-8a1759b5b882"><b id="docs-internal-guid-65a2c08e-58b3-c519-8857-7e278c044476"><div style="line-height: 1.2; margin-top: 0pt; margin-bottom: 0pt; "><span style="font-size: 13px; font-family: Arial; vertical-align: baseline; white-space: pre-wrap; ">The Xenopus ORFeome is here!</span></div><div style="line-height: 1.2; margin-top: 0pt; margin-bottom: 0pt; "><span style="font-size: 13px; font-family: Arial; font-weight: normal; vertical-align: baseline; white-space: pre-wrap; ">The </span><a href="http://www.xenbase.org/reagents/static/orfeome.jsp" style="text-decoration:none;"><span style="font-size: 13px; font-family: Arial; color: rgb(17, 85, 204); font-weight: normal; text-decoration: underline; vertical-align: baseline; white-space: pre-wrap; ">Xenopus ORFeome</span></a><span style="font-size: 13px; font-family: Arial; font-weight: normal; vertical-align: baseline; white-space: pre-wrap; "> is a collection of ~9,000 PCR-amplified ORFs from the </span><a href="http://xgc.nci.nih.gov/" style="text-decoration:none;"><span style="font-size: 13px; font-family: Arial; color: rgb(17, 85, 204); font-weight: normal; text-decoration: underline; vertical-align: baseline; white-space: pre-wrap; ">Xenopus Gene Collection</span></a><span style="font-size: 13px; font-family: Arial; font-weight: normal; vertical-align: baseline; white-space: pre-wrap; "> cloned into Gateway entry plasmid vector, pDONR223. The ORFeome collection covers ~7,800 unique genes representing approximately 40% of the non-redundant </span><span style="font-size: 13px; font-family: Arial; font-weight: normal; font-style: italic; vertical-align: baseline; white-space: pre-wrap; ">X. laevis</span><span style="font-size: 13px; font-family: Arial; font-weight: normal; vertical-align: baseline; white-space: pre-wrap; "> genome. Human orthologs were identified for ~7,000 of the validated frog clones, and ~2,200 are associated with human diseases. The ORFeome clones are available as a complete set of 93, 96-well plates from Biodesign Institute, EXRC, GE Healthcare, Harvard Medical School, and Source Bioscience. The Xenopus ORFeome PIs are </span><a href="http://www.xenbase.org/community/person.do?method=display&personId=1311" style="text-decoration:none;"><span style="font-size: 13px; font-family: Arial; color: rgb(17, 17, 17); font-weight: normal; text-decoration: underline; vertical-align: baseline; white-space: pre-wrap; ">Todd Stukenberg</span></a><span style="font-size: 13px; font-family: Arial; font-weight: normal; vertical-align: baseline; white-space: pre-wrap; ">, </span><a href="http://www.xenbase.org/community/person.do?method=display&personId=1840" style="text-decoration:none;"><span style="font-size: 13px; font-family: Arial; color: rgb(17, 17, 17); font-weight: normal; text-decoration: underline; vertical-align: baseline; white-space: pre-wrap; ">David Hill</span></a><span style="font-size: 13px; font-family: Arial; font-weight: normal; vertical-align: baseline; white-space: pre-wrap; ">, </span><a href="http://www.xenbase.org/community/person.do?method=display&personId=960" style="text-decoration:none;"><span style="font-size: 13px; font-family: Arial; color: rgb(17, 17, 17); font-weight: normal; text-decoration: underline; vertical-align: baseline; white-space: pre-wrap; ">Michael Gilchrist</span></a><span style="font-size: 13px; font-family: Arial; font-weight: normal; vertical-align: baseline; white-space: pre-wrap; ">, and </span><a href="http://www.xenbase.org/community/person.do?method=display&personId=720" style="text-decoration:none;"><span style="font-size: 13px; font-family: Arial; color: rgb(17, 17, 17); font-weight: normal; text-decoration: underline; vertical-align: baseline; white-space: pre-wrap; ">Aaron Zorn</span></a><span style="font-size: 13px; font-family: Arial; font-weight: normal; vertical-align: baseline; white-space: pre-wrap; ">. (Supported by NIH/NICHD grant R01HD069352). </span></div><br><div style="line-height: 1.2; margin-top: 0pt; margin-bottom: 0pt; "><span style="font-size: 13px; font-family: Arial; vertical-align: baseline; white-space: pre-wrap; ">A new outbred </span><span style="font-size: 13px; font-family: Arial; font-style: italic; vertical-align: baseline; white-space: pre-wrap; ">Xenopus laevis</span><span style="font-size: 13px; font-family: Arial; vertical-align: baseline; white-space: pre-wrap; "> Genome- now online</span></div><div style="line-height: 1.2; margin-top: 0pt; margin-bottom: 0pt; "><span style="font-size: 13px; font-family: Arial; font-weight: normal; vertical-align: baseline; white-space: pre-wrap; ">The </span><a href="https://www.vbi.vt.edu/people/people-profile/Pawel-Michalak" style="text-decoration:none;"><span style="font-size: 13px; font-family: Arial; color: rgb(17, 85, 204); font-weight: normal; text-decoration: underline; vertical-align: baseline; white-space: pre-wrap; ">Michalak Lab</span></a><span style="font-size: 13px; font-family: Arial; font-weight: normal; vertical-align: baseline; white-space: pre-wrap; "> at Virginia Tech sequenced an outbred adult </span><span style="font-size: 13px; font-family: Arial; font-weight: normal; font-style: italic; vertical-align: baseline; white-space: pre-wrap; ">X. laevis</span><span style="font-size: 13px; font-family: Arial; font-weight: normal; vertical-align: baseline; white-space: pre-wrap; "> female (ZW) from the Southern Cape Region of South Africa (supplied by Xenopus Express). Illumina Hiseq and 454/Life Sciences sequencing platforms were used to obtain a ~2.67 Gb assembly on 871,573 scaffolds. Almost 30,000 gene models are annotated, with 13,705 mapped to genes. This is a new resource for comparative and population genomics providing insights into genome-scale polymorphisms. The outbred </span><span style="font-size: 13px; font-family: Arial; font-weight: normal; font-style: italic; vertical-align: baseline; white-space: pre-wrap; ">X. laevis</span><span style="font-size: 13px; font-family: Arial; font-weight: normal; vertical-align: baseline; white-space: pre-wrap; "> genome is now available in the </span><a href="http://gbrowse.xenbase.org/fgb2/gbrowse/xl_wt1_0/?" style="text-decoration:none;"><span style="font-size: 13px; font-family: Arial; color: rgb(17, 85, 204); font-weight: normal; text-decoration: underline; vertical-align: baseline; white-space: pre-wrap; ">Xenbase genome browser</span></a><span style="font-size: 13px; font-family: Arial; font-weight: normal; vertical-align: baseline; white-space: pre-wrap; "> and can be queried via BLAST. </span></div><br><div style="line-height: 1.2; margin-top: 0pt; margin-bottom: 0pt; "><span style="font-size: 13px; font-family: Arial; vertical-align: baseline; white-space: pre-wrap; ">New Genome Browser Tracks</span></div><ul style="margin-top:0pt;margin-bottom:0pt;"><li dir="ltr" style="list-style-type: disc; font-size: 13px; font-family: Arial; font-weight: normal; vertical-align: baseline; "><div style="line-height: 1.2; margin-top: 0pt; margin-bottom: 0pt; "><span style="vertical-align: baseline; white-space: pre-wrap; ">NCBI tracks (</span><span style="font-style: italic; vertical-align: baseline; white-space: pre-wrap; ">X. tropicalis</span><span style="vertical-align: baseline; white-space: pre-wrap; "> v7.1) show alternative splicing, gene variants, pseudo genes and mirs/miRNAs</span></div></li><li dir="ltr" style="list-style-type: disc; font-size: 13px; font-family: Arial; font-weight: normal; vertical-align: baseline; "><div style="line-height: 1.2; margin-top: 0pt; margin-bottom: 0pt; "><span style="vertical-align: baseline; white-space: pre-wrap; ">new outbred Xenopus laevis genome</span></div></li><li dir="ltr" style="list-style-type: disc; font-size: 13px; font-family: Arial; font-weight: normal; vertical-align: baseline; "><div style="line-height: 1.2; margin-top: 0pt; margin-bottom: 0pt; "><span style="vertical-align: baseline; white-space: pre-wrap; ">genome details page has been re-vamped, allows downloadable FASTA files</span></div></li><li dir="ltr" style="list-style-type: disc; font-size: 13px; font-family: Arial; font-weight: normal; vertical-align: baseline; "><div style="line-height: 1.2; margin-top: 0pt; margin-bottom: 0pt; "><span style="vertical-align: baseline; white-space: pre-wrap; ">histone methylation,RNApol2, p300 CHiPseq data mapped to trop 7.1</span></div></li></ul><br><div style="line-height: 1.2; margin-top: 0pt; margin-bottom: 0pt; "><span style="font-size: 13px; font-family: Arial; vertical-align: baseline; white-space: pre-wrap; ">Data Download/FTP site: now more user-friendly </span></div><ul style="margin-top:0pt;margin-bottom:0pt;"><li dir="ltr" style="list-style-type: disc; font-size: 13px; font-family: Arial; font-weight: normal; vertical-align: baseline; "><div style="line-height: 1.2; margin-top: 0pt; margin-bottom: 0pt; "><span style="vertical-align: baseline; white-space: pre-wrap; ">Xenbase data exports and stored files are more easily accessible on our FTP/downloads page.</span></div></li><li dir="ltr" style="list-style-type: disc; font-size: 13px; font-family: Arial; font-weight: normal; vertical-align: baseline; "><div style="line-height: 1.2; margin-top: 0pt; margin-bottom: 0pt; "><span style="vertical-align: baseline; white-space: pre-wrap; ">Each file has a “readme” description associated detailing the contents and format(s) of the file. </span></div></li><li dir="ltr" style="list-style-type: disc; font-size: 13px; font-family: Arial; font-weight: normal; vertical-align: baseline; "><div style="line-height: 1.2; margin-top: 0pt; margin-bottom: 0pt; "><span style="vertical-align: baseline; white-space: pre-wrap; ">Field names for tab delimited files are contained in the readme information. </span></div></li><li dir="ltr" style="list-style-type: disc; font-size: 13px; font-family: Arial; font-weight: normal; vertical-align: baseline; "><div style="line-height: 1.2; margin-top: 0pt; margin-bottom: 0pt; "><span style="vertical-align: baseline; white-space: pre-wrap; ">Files organised by data type: gene reports, ChIP-seq, microarrray, movies/videos etc.</span></div></li></ul><br><div style="line-height: 1.2; margin-top: 0pt; margin-bottom: 0pt; "><span style="font-size: 13px; font-family: Arial; vertical-align: baseline; white-space: pre-wrap; ">Updates to the Xenopus genome editing online resources page</span></div><ul style="margin-top:0pt;margin-bottom:0pt;"><li dir="ltr" style="list-style-type: disc; font-size: 13px; font-family: Arial; font-weight: normal; vertical-align: baseline; "><div style="line-height: 1.2; margin-top: 0pt; margin-bottom: 0pt; "><span style="vertical-align: baseline; white-space: pre-wrap; ">CCTop now supports Xenla7.1 and XenTro3 genomes.</span></div></li><li dir="ltr" style="list-style-type: disc; font-size: 13px; font-family: Arial; font-weight: normal; vertical-align: baseline; "><div style="line-height: 1.2; margin-top: 0pt; margin-bottom: 0pt; "><span style="vertical-align: baseline; white-space: pre-wrap; ">GGGenome now supports:</span></div></li></ul><div style="line-height: 1.2; margin-top: 0pt; margin-bottom: 0pt; margin-left: 36pt; text-indent: 36pt; "><span style="font-size: 13px; font-family: Arial; font-weight: normal; vertical-align: baseline; white-space: pre-wrap; ">X. tropicalis v.7: </span><a href="http://gggenome.dbcls.jp/Xentr7/" style="text-decoration:none;"><span style="font-size: 13px; font-family: Arial; color: rgb(0, 0, 0); font-weight: normal; text-decoration: underline; vertical-align: baseline; white-space: pre-wrap; ">http://GGGenome.dbcls.jp/Xentr7/</span></a></div><div style="line-height: 1.2; margin-top: 0pt; margin-bottom: 0pt; margin-left: 36pt; text-indent: 36pt; "><span style="font-size: 13px; font-family: Arial; font-weight: normal; vertical-align: baseline; white-space: pre-wrap; ">X. tropicalis v.8: </span><a href="http://gggenome.dbcls.jp/Xentr8/" style="text-decoration:none;"><span style="font-size: 13px; font-family: Arial; color: rgb(0, 0, 0); font-weight: normal; text-decoration: underline; vertical-align: baseline; white-space: pre-wrap; ">http://GGGenome.dbcls.jp/Xentr8/</span></a></div><div style="line-height: 1.2; margin-top: 0pt; margin-bottom: 0pt; "><span style="font-size: 13px; font-family: Arial; font-weight: normal; vertical-align: baseline; white-space: pre-wrap; ">Additional details can be seen at: </span><a href="http://www.xenbase.org/other/static/CRISPr.jsp" style="text-decoration:none;"><span style="font-size: 13px; font-family: Arial; color: rgb(0, 0, 0); font-weight: normal; text-decoration: underline; vertical-align: baseline; white-space: pre-wrap; ">http://www.xenbase.org/other/static/CRISPr.jsp</span></a></div><br><div style="line-height: 1.2; margin-top: 0pt; margin-bottom: 0pt; "><span style="font-size: 13px; font-family: Arial; vertical-align: baseline; white-space: pre-wrap; ">New </span><span style="font-size: 13px; font-family: Arial; font-style: italic; vertical-align: baseline; white-space: pre-wrap; ">Xenopus laevis</span><span style="font-size: 13px; font-family: Arial; vertical-align: baseline; white-space: pre-wrap; "> </span><a href="http://www.xenbase.org/gene/static/chromosomeNomenclature.jsp" style="text-decoration:none;"><span style="font-size: 13px; font-family: Arial; color: rgb(17, 85, 204); text-decoration: underline; vertical-align: baseline; white-space: pre-wrap; ">Chromosome Nomenclature</span></a></div><div style="line-height: 1.2; margin-top: 0pt; margin-bottom: 0pt; "><span style="font-size: 13px; font-family: Arial; font-weight: normal; font-style: italic; vertical-align: baseline; white-space: pre-wrap; ">Xenopus laevis</span><span style="font-size: 13px; font-family: Arial; font-weight: normal; vertical-align: baseline; white-space: pre-wrap; "> is allotetraploid and has 36 chromosomes consisting of 2 sets of 18 chromosomes. The new chromosome nomenclature for </span><span style="font-size: 13px; font-family: Arial; font-weight: normal; font-style: italic; vertical-align: baseline; white-space: pre-wrap; ">X. laevis</span><span style="font-size: 13px; font-family: Arial; font-weight: normal; vertical-align: baseline; white-space: pre-wrap; "> is based on phylogenetic relationship and chromosome length, i.e. XLA1L, XLA1S, XLA1L, XLA2S, etc. in which the numbering of XLA chromosomes corresponds to the diploid </span><span style="font-size: 13px; font-family: Arial; font-weight: normal; font-style: italic; vertical-align: baseline; white-space: pre-wrap; ">X. tropicalis</span><span style="font-size: 13px; font-family: Arial; font-weight: normal; vertical-align: baseline; white-space: pre-wrap; ">. The postfixes ‘L’ and ‘S’ stand for long and short chromosomal homeologous pairs. The last </span><span style="font-size: 13px; font-family: Arial; font-weight: normal; font-style: italic; vertical-align: baseline; white-space: pre-wrap; ">X. laevis</span><span style="font-size: 13px; font-family: Arial; font-weight: normal; vertical-align: baseline; white-space: pre-wrap; "> chromosome set, XLA9L and XLA9S, corresponds to fused XTR9 and XTR10, with XLA9_10L and XLA9_10S as synonyms. </span><span style="font-size: 13px; font-family: Arial; color: rgb(34, 34, 34); font-weight: normal; vertical-align: baseline; white-space: pre-wrap; ">See: Matsuda et al., </span><a href="http://www.ncbi.nlm.nih.gov/pubmed/25871511#" style="text-decoration:none;"><span style="font-size: 13px; font-family: Arial; color: rgb(17, 85, 204); font-weight: normal; text-decoration: underline; vertical-align: baseline; white-space: pre-wrap; ">Cytogenet Genome Res.</span></a><span style="font-size: 13px; font-family: Arial; color: rgb(34, 34, 34); font-weight: normal; vertical-align: baseline; white-space: pre-wrap; "> 2015 Apr 8. for more details.</span></div><br><div style="line-height: 1.2; margin-top: 0pt; margin-bottom: 0pt; "><span style="font-size: 13px; font-family: Arial; color: rgb(34, 34, 34); vertical-align: baseline; white-space: pre-wrap; ">Congratulations to the newly elected members of the National Academy of Sciences:</span></div><br><div style="line-height: 1.2; margin-top: 0pt; margin-bottom: 0pt; "><a href="http://www.bbe.caltech.edu/content/marianne-bronner" style="text-decoration:none;"><span style="font-size: 13px; font-family: Arial; color: rgb(17, 85, 204); background-color: rgb(255, 255, 255); font-style: italic; text-decoration: underline; vertical-align: baseline; white-space: pre-wrap; ">Marianne Bronner: </span></a><span style="font-size: 13px; font-family: Arial; background-color: rgb(255, 255, 255); font-weight: normal; vertical-align: baseline; white-space: pre-wrap; ">California Institute of Technology, Pasadena, CA, USA.</span></div><div style="line-height: 1.2; margin-top: 0pt; margin-bottom: 0pt; "><a href="http://depts.washington.edu/phcol/faculty/moon.php" style="text-decoration:none;"><span style="font-size: 13px; font-family: Arial; color: rgb(17, 85, 204); background-color: rgb(255, 255, 255); font-style: italic; text-decoration: underline; vertical-align: baseline; white-space: pre-wrap; ">Randall Moon</span><span style="font-size: 13px; font-family: Arial; color: rgb(17, 85, 204); background-color: rgb(255, 255, 255); font-weight: normal; text-decoration: underline; vertical-align: baseline; white-space: pre-wrap; ">;</span></a><span style="font-size: 13px; font-family: Arial; background-color: rgb(255, 255, 255); font-weight: normal; vertical-align: baseline; white-space: pre-wrap; "> University of Washington, Seattle, WA, USA</span></div><div style="line-height: 1.2; margin-top: 0pt; margin-bottom: 0pt; "><a href="http://life-sci.ust.hk/faculty/Prof.N.Ip/" style="text-decoration:none;"><span style="font-size: 13px; font-family: Arial; color: rgb(17, 85, 204); background-color: rgb(255, 255, 255); font-style: italic; text-decoration: underline; vertical-align: baseline; white-space: pre-wrap; ">Nancy Ip</span><span style="font-size: 13px; font-family: Arial; color: rgb(17, 85, 204); background-color: rgb(255, 255, 255); font-weight: normal; text-decoration: underline; vertical-align: baseline; white-space: pre-wrap; ">:</span></a><span style="font-size: 13px; font-family: Arial; background-color: rgb(255, 255, 255); font-weight: normal; vertical-align: baseline; white-space: pre-wrap; "> Hong Kong University of Science and Technology, Kowloon, Hong Kong (China).</span></div><br><div style="line-height: 1.2; margin-top: 0pt; margin-bottom: 0pt; "><a href="http://forums.xenbase.org/phpBB3/" style="text-decoration:none;"><span style="font-size: 13px; font-family: Arial; color: rgb(17, 85, 204); background-color: rgb(255, 255, 255); text-decoration: underline; vertical-align: baseline; white-space: pre-wrap; ">Xenbase Forums</span></a><span style="font-size: 13px; font-family: Arial; background-color: rgb(255, 255, 255); font-weight: normal; vertical-align: baseline; white-space: pre-wrap; "> is the Xenopus community forum - a great place to seek answers to the day-to-day Xenopus life-hacks, dealing with difficult wet lab experiments, frog room drama, pesky reagents, - whatever you need help with - as your community!</span></div><br></b><div><span style="font-size: 13px; font-family: Arial; background-color: rgb(255, 255, 255); font-weight: normal; vertical-align: baseline; white-space: pre-wrap; "><br></span></div></b></div></b></div></b><div apple-content-edited="true"><span class="Apple-style-span" style="border-collapse: separate; border-spacing: 0px; "><b id="docs-internal-guid-65a2c08e-58b6-ad24-8fed-a702bd7674c1"><div style="line-height: 1.2; margin-top: 0pt; margin-bottom: 0pt; "><b id="docs-internal-guid-65a2c08e-58b7-3c9e-cbca-ed6252042cd9"><div style="line-height: 1.2; margin-top: 0pt; margin-bottom: 0pt; "><span style="font-size: 13px; font-family: Arial; background-color: rgb(255, 255, 255); font-style: italic; vertical-align: baseline; white-space: pre-wrap; ">Interested in submitting gene expression or other data sets to Xenbase?</span></div><div style="line-height: 1.2; margin-top: 0pt; margin-bottom: 0pt; "><span style="font-size: 13px; font-family: Arial; background-color: rgb(255, 255, 255); font-weight: normal; vertical-align: baseline; white-space: pre-wrap; ">Contact the curation team: <a href="mailto:xenbase@ucalgary.ca">xenbase@ucalgary.ca</a></span></div><div><span style="font-size: 13px; font-family: Arial; background-color: rgb(255, 255, 255); font-weight: normal; vertical-align: baseline; white-space: pre-wrap; "><br></span></div></b></div><div><span style="font-size: 13px; font-family: Arial; background-color: rgb(255, 255, 255); font-weight: normal; vertical-align: baseline; white-space: pre-wrap; "><br></span></div></b><span style="color: rgb(0, 0, 0); font-family: 'Helvetica Neue'; font-size: medium; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: normal; orphans: 2; text-align: -webkit-auto; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-size-adjust: auto; -webkit-text-stroke-width: 0px; "></span><span style="color: rgb(0, 0, 0); font-family: 'Helvetica Neue'; font-size: medium; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: normal; orphans: 2; text-align: -webkit-auto; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-size-adjust: auto; -webkit-text-stroke-width: 0px; "></span><span style="color: rgb(0, 0, 0); font-family: 'Helvetica Neue'; font-size: medium; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: normal; orphans: 2; text-align: -webkit-auto; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-size-adjust: auto; -webkit-text-stroke-width: 0px; "></span><span style="color: rgb(0, 0, 0); font-family: 'Helvetica Neue'; font-size: medium; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: normal; orphans: 2; text-align: -webkit-auto; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-size-adjust: auto; -webkit-text-stroke-width: 0px; "><span><img height="48" width="256" id="b426b937-5ab5-4d9f-ae7e-e83e9146b1cd" apple-width="yes" apple-height="yes" src="cid:3393311928_31261500"></span><span class="Apple-style-span" style="border-collapse: separate; border-spacing: 0px; "><span class="Apple-style-span" style="border-collapse: separate; color: rgb(0, 0, 0); font-family: 'Helvetica Neue'; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: normal; orphans: 2; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; border-spacing: 0px; -webkit-text-decorations-in-effect: none; -webkit-text-size-adjust: auto; -webkit-text-stroke-width: 0px; font-size: medium; "><span class="Apple-style-span" style="border-collapse: separate; color: rgb(0, 0, 0); font-family: 'Helvetica Neue'; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: normal; orphans: 2; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; border-spacing: 0px; -webkit-text-decorations-in-effect: none; -webkit-text-size-adjust: auto; -webkit-text-stroke-width: 0px; font-size: medium; "><br><a href="http://www.xenbase.org">http://www.xenbase.org</a><br></span></span></span>
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