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<p class="MsoNormal"><span style="font-size:14.0pt">Attention Xenopus researchers,<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt"><o:p>&nbsp;</o:p></span></p>
<p class="MsoNormal"><span style="font-family:&quot;Arial&quot;,sans-serif;color:black">As Co-Director of
</span><a href="https://www.xenbase.org/entry/"><span style="font-family:&quot;Arial&quot;,sans-serif">Xenbase</span></a><span style="font-family:&quot;Arial&quot;,sans-serif;color:black">, I am reaching out to
<b>researchers who use <i>Xenopus</i></b> as a model, particularly those funded by the NIH, to ask for
<b>your support</b>. The renewal of the Xenbase grant (P41 HD064556) through the NIH, is due in May 2020. If the continued existence of Xenbase is important for your research, we ask you
<b>write a letter of support</b>. </span><span style="font-family:&quot;Times New Roman&quot;,serif"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:&quot;Arial&quot;,sans-serif;color:black"><o:p>&nbsp;</o:p></span></p>
<p class="MsoNormal"><span style="font-family:&quot;Arial&quot;,sans-serif;color:black">Many of you will have already received an email from me. If you haven’t yet responded- consider this a reminder! &nbsp;Thank you to those who already have sent a LoS- it is great to know
 Xenbase is essential to so many labs, but we need to hear from more people.<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:&quot;Arial&quot;,sans-serif;color:black"><o:p>&nbsp;</o:p></span></p>
<p class="MsoNormal"><span style="font-family:&quot;Arial&quot;,sans-serif;color:black">If this is you first time you have heard from us,
<b>please write a Letter of Support</b>. <o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:&quot;Arial&quot;,sans-serif;color:black"><o:p>&nbsp;</o:p></span></p>
<p class="MsoNormal"><span style="font-family:&quot;Arial&quot;,sans-serif;color:black">Hopefully, will be collecting hundreds of letters, so we need you
<b>to write the letters in your own words</b>. To make this as easy as possible for you, we’ve provided a template [below] with ideas of what to include in the letter of support.
<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:&quot;Arial&quot;,sans-serif;color:black"><o:p>&nbsp;</o:p></span></p>
<p class="MsoNormal"><b><span style="font-family:&quot;Arial&quot;,sans-serif;color:black">Please reply to this Xenbase email (</span><a href="mailto:Xenbase@cchmc.org"><span style="font-family:&quot;Arial&quot;,sans-serif">Xenbase@cchmc.org</span></a></b><b><span style="font-family:&quot;Arial&quot;,sans-serif;color:black">)
 with your letter, ideally by the mid-March 2020</span></b><span style="font-family:&quot;Arial&quot;,sans-serif;color:black">, although we are happy to receive it sooner!
<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:&quot;Arial&quot;,sans-serif;color:black"><o:p>&nbsp;</o:p></span></p>
<p class="MsoNormal"><span style="font-family:&quot;Arial&quot;,sans-serif;color:black">Many thanks,<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:&quot;Arial&quot;,sans-serif;color:black"><o:p>&nbsp;</o:p></span></p>
<p class="MsoNormal"><span style="font-family:&quot;Arial&quot;,sans-serif;color:black">Aaron Zorn<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt"><o:p>&nbsp;</o:p></span></p>
<p class="MsoNormal"><b><span style="font-size:11.0pt;font-family:&quot;Arial&quot;,sans-serif;color:#287189">Aaron Zorn PhD</span></b><span style="font-size:11.0pt;color:black"><o:p></o:p></span></p>
<p class="MsoNormal"><i><span style="font-size:11.0pt;font-family:&quot;Arial&quot;,sans-serif;color:#287189">Co-Director Xenbase</span></i><span style="font-size:11.0pt;color:black"><o:p></o:p></span></p>
<p class="MsoNormal"><i><span style="font-size:11.0pt;font-family:&quot;Arial&quot;,sans-serif;color:#287189">Professor of Pediatrics</span></i><span style="font-size:11.0pt;color:black"><o:p></o:p></span></p>
<p class="MsoNormal"><i><span style="font-size:11.0pt;font-family:&quot;Arial&quot;,sans-serif;color:#287189">Division of Developmental Biology</span></i><span style="font-size:11.0pt;color:black"><o:p></o:p></span></p>
<p class="MsoNormal"><a href="http://www.xenbase.org/" title="http://www.xenbase.org/"><span style="font-size:11.0pt;font-family:&quot;Arial&quot;,sans-serif;color:#0000E9">http://www.xenbase.org</span></a><span style="font-size:11.0pt;color:black"><o:p></o:p></span></p>
<p class="MsoNormal"><b><span style="font-size:11.0pt;font-family:&quot;Arial&quot;,sans-serif;color:black">Cincinnati Children’s</span></b><span style="font-size:11.0pt;color:black"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:&quot;Arial&quot;,sans-serif;color:#6D6D6D">240 Sabin Way&nbsp;</span><span style="font-size:11.0pt;font-family:&quot;Arial&quot;,sans-serif;color:gray">R3.566</span><span style="font-size:11.0pt;font-family:&quot;Arial&quot;,sans-serif;color:#6D6D6D">,
 Cincinnati OH 45229</span><span style="font-size:11.0pt;color:black"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:&quot;Arial&quot;,sans-serif;color:#6D6D6D">Phone: 1.513.636.3770</span><span style="font-size:11.0pt;color:black"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:&quot;Verdana&quot;,sans-serif;color:black">&nbsp;</span><span style="font-size:11.0pt;color:black"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:&quot;Verdana&quot;,sans-serif;color:black"><img border="0" width="256" height="48" style="width:2.6666in;height:.5in" id="_x0000_i1025" src="cid:image001.png@01D5F08B.CC945050"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:&quot;Verdana&quot;,sans-serif;color:black"><o:p>&nbsp;</o:p></span></p>
<p class="MsoNormal"><b><span style="font-family:&quot;Arial&quot;,sans-serif;color:black">Template Letter,&nbsp; Xenbase Renewal:</span></b><span style="color:black"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:&quot;Arial&quot;,sans-serif;color:black">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
</span><span style="color:black"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:&quot;Arial&quot;,sans-serif;color:black">Dear Drs. Aaron Zorn and Peter Vize,
</span><span style="color:black"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:&quot;Arial&quot;,sans-serif;color:black">Directors, Xenbase</span><span style="color:black"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:&quot;Arial&quot;,sans-serif;color:black">&nbsp;</span><span style="color:black"><o:p></o:p></span></p>
<ul type="disc">
<li class="MsoListParagraph" style="color:black;mso-list:l0 level1 lfo1"><span style="font-family:&quot;Arial&quot;,sans-serif">Express your support for the Xenbase renewal.</span><span style="font-family:&quot;Calibri&quot;,sans-serif"><o:p></o:p></span></li><li class="MsoListParagraph" style="mso-list:l0 level1 lfo1"><span style="font-family:&quot;Arial&quot;,sans-serif;color:black">Mention how renewal of Xenbase was identified as the most important immediate need of the Xenopus Research Community in the
</span><a href="https://www.xenbase.org/entry/doNewsRead.do?id=699"><span style="font-family:&quot;Arial&quot;,sans-serif">2020 Xenopus White Paper</span></a><span style="font-family:&quot;Arial&quot;,sans-serif;color:black">.</span><o:p></o:p></li><li class="MsoListParagraph" style="color:black;mso-list:l0 level1 lfo1"><span style="font-family:&quot;Arial&quot;,sans-serif">Briefly, describe your research (listing previous and current NIH grants).</span><span style="font-family:&quot;Calibri&quot;,sans-serif"><o:p></o:p></span></li><li class="MsoListParagraph" style="color:black;mso-list:l0 level1 lfo1"><span style="font-family:&quot;Arial&quot;,sans-serif">Explain how important is Xenbase to your research.</span><span style="font-family:&quot;Calibri&quot;,sans-serif"><o:p></o:p></span></li><li class="MsoListParagraph" style="color:black;mso-list:l0 level1 lfo1"><span style="font-family:&quot;Arial&quot;,sans-serif">Describe which features of Xenbase that your lab uses and how frequently you use Xenbase (how many times a day?).</span><span style="font-family:&quot;Calibri&quot;,sans-serif"><o:p></o:p></span></li><li class="MsoListParagraph" style="color:black;mso-list:l0 level1 lfo1"><span style="font-family:&quot;Arial&quot;,sans-serif">Possible features to emphasize: genomes and genomics, support for human disease modeling, data sharing infrastructure for special community
 resources, expression curation, reagents etc.&nbsp;</span><span style="font-family:&quot;Calibri&quot;,sans-serif"><o:p></o:p></span></li><li class="MsoListParagraph" style="color:black;mso-list:l0 level1 lfo1"><span style="font-family:&quot;Arial&quot;,sans-serif">How does Xenbase compare to other model organism databases that you use?</span><span style="font-family:&quot;Calibri&quot;,sans-serif"><o:p></o:p></span></li><li class="MsoListParagraph" style="color:black;mso-list:l0 level1 lfo1"><span style="font-family:&quot;Arial&quot;,sans-serif">Finally, explain how your research would be impacted if Xenbase ceased to exist.<o:p></o:p></span></li></ul>
<p class="MsoNormal" style="margin-left:.75in;text-indent:-.5in"><span style="font-family:&quot;Arial&quot;,sans-serif;color:black"><o:p>&nbsp;</o:p></span></p>
<p class="MsoNormal" style="margin-left:.5in;text-indent:-.5in"><span style="font-family:&quot;Arial&quot;,sans-serif;color:black"><o:p>&nbsp;</o:p></span></p>
<p class="MsoNormal" style="margin-left:.5in;text-indent:-.5in"><span style="font-family:&quot;Arial&quot;,sans-serif;color:black">Signature<o:p></o:p></span></p>
<p class="MsoNormal" style="margin-left:.5in;text-indent:-.5in"><span style="font-family:&quot;Arial&quot;,sans-serif;color:black">Position<o:p></o:p></span></p>
<p class="MsoNormal" style="margin-left:.5in;text-indent:-.5in"><span style="font-family:&quot;Arial&quot;,sans-serif;color:black">Institute/Affiliation<o:p></o:p></span></p>
<p class="MsoNormal" style="margin-left:.5in;text-indent:-.5in"><span style="font-family:&quot;Arial&quot;,sans-serif;color:black">Contact details<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt"><o:p>&nbsp;</o:p></span></p>
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