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<p style="margin:0in"><span style="font-size:12.0pt;font-family:&quot;Arial&quot;,sans-serif;color:#444342">Have you published a paper that describes outstanding and original work that has or could have major impacts on the replacement, reduction or refinement of the
 use of animals in research? <o:p></o:p></span></p>
<p style="margin:0in"><span style="font-size:12.0pt;font-family:&quot;Arial&quot;,sans-serif;color:#444342"><o:p>&nbsp;</o:p></span></p>
<p style="margin:0in"><span style="font-size:12.0pt;font-family:&quot;Arial&quot;,sans-serif;color:#444342">If so, then you should apply for the annual
<b>NC3Rs prize</b> which is sponsored by GSK to recognise a paper published in the last 3 years with demonstrable 3Rs impacts.<o:p></o:p></span></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><span style="font-size:12.0pt;font-family:&quot;Arial&quot;,sans-serif;color:#212121">There is a lot of amazing science happening in the
<i>Xenopus</i> community with great 3Rs </span><span style="font-size:12.0pt;font-family:&quot;Arial&quot;,sans-serif;color:black">potential!&nbsp;
<o:p></o:p></span></p>
<p class="MsoNormal" style="margin-top:15.0pt"><b><span style="font-size:14.0pt;font-family:&quot;Arial&quot;,sans-serif;color:black;letter-spacing:-.4pt">International 3Rs prize<o:p></o:p></span></b></p>
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:&quot;Arial&quot;,sans-serif;color:black">An annual prize awarded for a paper that describes outstanding and original work that has or could have major impacts on the replacement, reduction or refinement
 of the use of animals in research.<o:p></o:p></span></p>
<p style="mso-margin-top-alt:15.0pt;margin-right:0in;margin-bottom:0in;margin-left:0in">
<span style="font-size:12.0pt;font-family:&quot;Arial&quot;,sans-serif;color:#444342">This prestigious award consists of a £28k prize grant* and a £2k personal award.<o:p></o:p></span></p>
<p style="mso-margin-top-alt:15.0pt;margin-right:0in;margin-bottom:0in;margin-left:0in;box-sizing: inherit;caret-color: rgb(68, 67, 66);font-variant-caps: normal;orphans: auto;text-align:start;widows: auto;-webkit-text-size-adjust: auto;-webkit-text-stroke-width: 0px;word-spacing:0px">
<span style="font-size:12.0pt;font-family:&quot;Arial&quot;,sans-serif;color:#444342">*£20k is provided by GSK with the remaining funds provided by the NC3Rs.<o:p></o:p></span></p>
<p style="mso-margin-top-alt:15.0pt;margin-right:0in;margin-bottom:0in;margin-left:0in">
<span style="font-size:12.0pt;font-family:&quot;Arial&quot;,sans-serif;color:#444342"><o:p>&nbsp;</o:p></span></p>
<p class="MsoNormal" style="background:#F4F4F4"><span style="font-size:12.0pt;font-family:&quot;Arial&quot;,sans-serif;color:#444342">This year's competition is now open.
<o:p></o:p></span></p>
<p class="MsoNormal" style="background:#F4F4F4"><span style="font-size:12.0pt;font-family:&quot;Arial&quot;,sans-serif;color:#444342"><o:p>&nbsp;</o:p></span></p>
<p class="MsoNormal" style="background:#F4F4F4"><span style="font-size:12.0pt;font-family:&quot;Arial&quot;,sans-serif;color:#444342">The deadline to submit your application is&nbsp;<strong><span style="font-family:&quot;Arial&quot;,sans-serif">Wednesday 5 April 2023.</span></strong><o:p></o:p></span></p>
<p style="mso-margin-top-alt:15.0pt;margin-right:0in;margin-bottom:0in;margin-left:0in;box-sizing: inherit;caret-color: rgb(68, 67, 66);font-variant-caps: normal;orphans: auto;text-align:start;widows: auto;-webkit-text-size-adjust: auto;-webkit-text-stroke-width: 0px;word-spacing:0px">
<span style="font-size:12.0pt;font-family:&quot;Arial&quot;,sans-serif;color:#444342">For further information on the 3Rs prize, please contact&nbsp;<a href="mailto:3rsprize@nc3rs.org.uk?subject=3Rs%20Prize"><b><span style="color:#444342">3Rsprize@nc3rs.org.uk</span></b></a>.<o:p></o:p></span></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><span style="font-size:12.0pt;color:black">Full details on website:&nbsp;
</span><span style="font-size:12.0pt;font-family:&quot;Arial&quot;,sans-serif;color:#212121"><a href="https://nc3rs.org.uk/international-3rs-prize">https://nc3rs.org.uk/international-3rs-prize</a></span><span style="font-size:12.0pt;color:black"><o:p></o:p></span></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><span style="font-size:12.0pt;font-family:&quot;Arial&quot;,sans-serif;color:#212121">&nbsp;</span><span style="font-size:12.0pt;color:#212121"><o:p></o:p></span></p>
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<span style="font-size:12.0pt;font-family:&quot;Arial&quot;,sans-serif;color:#212121">Best wishes,</span><span style="font-size:12.0pt;color:#212121"><o:p></o:p></span></p>
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<span style="font-size:12.0pt;font-family:&quot;Arial&quot;,sans-serif;color:#212121">Esther</span><span style="font-size:12.0pt;color:#212121"><o:p></o:p></span></p>
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<span style="font-size:12.0pt;font-family:&quot;Arial&quot;,sans-serif;color:#212121">&nbsp;</span><span style="font-size:12.0pt;color:#212121"><o:p></o:p></span></p>
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<b><span style="font-size:12.0pt;font-family:&quot;Arial&quot;,sans-serif;color:#404040">Dr Esther Pearl<span class="apple-converted-space">&nbsp;</span></span></b><i><span style="font-size:12.0pt;font-family:&quot;Arial&quot;,sans-serif;color:#404040">(she/her)</span></i><b><span style="font-size:12.0pt;font-family:&quot;Arial&quot;,sans-serif;color:#404040"><br>
Programme Manager - Experimental Design<br>
NC3Rs – National Centre for the Replacement, Refinement and Reduction of Animals in Research</span></b><span style="font-size:12.0pt;color:#212121"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:&quot;Times New Roman&quot;,serif;color:black"><o:p>&nbsp;</o:p></span></p>
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