<html xmlns:v="urn:schemas-microsoft-com:vml" xmlns:o="urn:schemas-microsoft-com:office:office" xmlns:w="urn:schemas-microsoft-com:office:word" xmlns:m="http://schemas.microsoft.com/office/2004/12/omml" xmlns="http://www.w3.org/TR/REC-html40">
<head>
<meta http-equiv="Content-Type" content="text/html; charset=Windows-1252">
<meta name="Generator" content="Microsoft Word 15 (filtered medium)">
<!--[if !mso]><style>v\:* {behavior:url(#default#VML);}
o\:* {behavior:url(#default#VML);}
w\:* {behavior:url(#default#VML);}
.shape {behavior:url(#default#VML);}
</style><![endif]--><style><!--
/* Font Definitions */
@font-face
{font-family:"Cambria Math";
panose-1:2 4 5 3 5 4 6 3 2 4;}
@font-face
{font-family:Calibri;
panose-1:2 15 5 2 2 2 4 3 2 4;}
@font-face
{font-family:Aptos;
panose-1:2 11 0 4 2 2 2 2 2 4;}
@font-face
{font-family:"Times New Roman \(Textkörper CS\)";
panose-1:2 11 6 4 2 2 2 2 2 4;}
@font-face
{font-family:Palatino;
panose-1:0 0 0 0 0 0 0 0 0 0;}
@font-face
{font-family:"Gill Sans MT";
panose-1:2 11 5 2 2 1 4 2 2 3;}
/* Style Definitions */
p.MsoNormal, li.MsoNormal, div.MsoNormal
{margin:0cm;
font-size:11.0pt;
font-family:"Aptos",sans-serif;
mso-ligatures:standardcontextual;
mso-fareast-language:EN-US;}
a:link, span.MsoHyperlink
{mso-style-priority:99;
color:#467886;
text-decoration:underline;}
span.E-MailFormatvorlage17
{mso-style-type:personal-compose;
font-family:"Arial",sans-serif;
color:windowtext;}
.MsoChpDefault
{mso-style-type:export-only;
font-size:11.0pt;
mso-fareast-language:EN-US;}
@page WordSection1
{size:612.0pt 792.0pt;
margin:70.85pt 70.85pt 2.0cm 70.85pt;}
div.WordSection1
{page:WordSection1;}
--></style>
</head>
<body lang="DE-CH" link="#467886" vlink="#96607D" style="word-wrap:break-word">
<div class="WordSection1">
<div>
<div>
<p class="MsoNormal" align="center" style="margin-bottom:16.0pt;text-align:center">
<b><span lang="EN-US" style="font-size:14.0pt">Postdoctoral Scientist in Biomedical Research 100%. <img width="152" height="152" style="width:1.5833in;height:1.5833in" id="Grafik_x0020_1" src="cid:image001.jpg@01DBC583.6DBE5760"><o:p></o:p></span></b></p>
<p class="MsoNormal" style="margin-bottom:7.5pt;line-height:15.75pt"><b><span lang="EN-US" style="font-size:13.5pt;font-family:Palatino;color:#0028A5;mso-fareast-language:DE">Introduction:
<o:p></o:p></span></b></p>
<p class="MsoNormal" style="text-align:justify"><span lang="EN-US">The institute of Anatomy at the University of Zurich combines modern biomedical research with training the next generation of medical professionals. As a postdoctoral researcher, you will join
a team focused on using amphibian models (<i>Xenopus tropicalis</i> and <i>laevis</i>) to explore the molecular mechanisms of inherited diseases, a dynamic field, where your contribution can make a real difference.<o:p></o:p></span></p>
<p class="MsoNormal" style="text-align:justify"><span lang="EN-US"><o:p> </o:p></span></p>
<p class="MsoNormal" style="text-align:justify"><span lang="EN-US">We recently pioneered new tools for targeted genomic integration to generate custom transgenic lines and endogenously tag proteins of interest (</span><a href="https://doi.org/10.1101/2024.09.23.614424"><span lang="EN-US">Naert,
et al., BioRxiv, 2024</span></a><span lang="EN-US">)</span><span lang="EN-US" style="font-family:"Gill Sans MT",sans-serif;color:#333333;background:white">. We will employ these tools in combination with advanced imaging techniques and analysis tools (</span><a href="https://doi.org/10.1242/dev.199664"><span lang="EN-US" style="font-family:"Gill Sans MT",sans-serif;background:white">Naert,
et al., Development, 2021</span></a><span lang="EN-US" style="font-family:"Gill Sans MT",sans-serif;color:#333333;background:white">) to explore the
<i>in vivo</i> functions of proteins related to congenital diseases, including genetic kidney diseases and ciliopathies.</span><span lang="EN-US"><o:p></o:p></span></p>
<p class="MsoNormal" style="margin-bottom:7.5pt;line-height:15.75pt"><b><span lang="EN-US" style="font-size:13.5pt;font-family:Palatino;color:#0028A5;mso-fareast-language:DE"><o:p> </o:p></span></b></p>
<p class="MsoNormal" style="margin-bottom:7.5pt;line-height:15.75pt"><b><span lang="EN-US" style="font-size:13.5pt;font-family:Palatino;color:#0028A5;mso-fareast-language:DE">Your responsibilities<o:p></o:p></span></b></p>
<p class="MsoNormal" style="text-align:justify"><span lang="EN-US">Your main objective will be to conduct innovative research into the molecular mechanisms of genetic diseases employing novel models and genome engineering in
<i>Xenopus</i>. You will use key technologies, such as light-sheet imaging, live imaging, automated image analysis, CRISPR knockout or integration in
<i>Xenopus</i> embryos. You are welcome to contribute your own ideas and actively shape the project.<o:p></o:p></span></p>
<p class="MsoNormal" style="text-align:justify"><span lang="EN-US">You will work in collaboration with PhD candidates and supervise junior group members or Master students. You will also be introduced to and participate in the teaching activities of the Institute
(i.e. Practical Laboratory and Histology courses) to gain academic teaching credentials.<o:p></o:p></span></p>
<p class="MsoNormal" style="margin-bottom:7.5pt;line-height:15.75pt"><b><span lang="EN-US" style="font-size:13.5pt;font-family:Palatino;color:#0028A5;mso-fareast-language:DE"><o:p> </o:p></span></b></p>
<p class="MsoNormal" style="margin-bottom:7.5pt;line-height:15.75pt"><b><span lang="EN-US" style="font-size:13.5pt;font-family:Palatino;color:#0028A5;mso-fareast-language:DE">Your profile<o:p></o:p></span></b></p>
<p class="MsoNormal" style="text-align:justify"><span lang="EN-US">We are looking forward to applications from highly motivated researchers (m/w/d), who hold a PhD degree in life sciences or a medical degree with at least one publication as first author in
a high quality, peer reviewed journal. MD-PhDs with a strong affinity to the natural sciences can be excellent candidates. You should have the ability to work both independently and team oriented, be proficient in English, and have excellent project management
and communication skills. Experience with aquatic models, imaging techniques, and teaching experience are a plus. What we value most, however, are commitment, reliability, and – above all – a genuine curiosity and interest in research.<o:p></o:p></span></p>
<p class="MsoNormal" style="margin-bottom:4.0pt;text-autospace:none"><b><span lang="EN-US"><o:p> </o:p></span></b></p>
<p class="MsoNormal" style="margin-bottom:7.5pt;line-height:15.75pt"><b><span lang="EN-US" style="font-size:13.5pt;font-family:Palatino;color:#0028A5;mso-fareast-language:DE">What we offer<o:p></o:p></span></b></p>
<p class="MsoNormal" style="text-align:justify"><span lang="EN-US">Our collaborative, well-funded research team values communication, and an inspiring work environment. We offer an exciting research project in a clinically relevant field funded by the SNSF.
We have a track record of uncovering pathomechanisms of genetic disease (</span><a href="https://doi.org/10.1038/ng.2681"><span lang="EN-US">Hoff et al., Nat. Genetics, 2013</span></a><span lang="EN-US">;
</span><a href="https://doi.org/10.1073/pnas.2106770118"><span lang="EN-US">Getwan, et al., PNAS, 2021</span></a><span lang="EN-US">) and technological advancements (</span><a href="https://doi.org/10.1038/s41587-023-01717-8"><span lang="EN-US">Voigt et al.,
Nat. Biotech, 2024</span></a><span lang="EN-US">; </span><a href="https://doi.org/10.1038/s41467-024-46770-2"><span lang="EN-US">Vladimirov, et al., Nat. Comm, 2024</span></a><span lang="EN-US">).<o:p></o:p></span></p>
<p class="MsoNormal" style="text-align:justify"><span lang="EN-US">Our group is well integrated in the local research environment, member of the Zurich Kidney Center, and well connected to the international Kidney and
<i>Xenopus</i> communities, with access to outstanding scientific infrastructure and core facilities at both the University of Zurich and the ETH Zurich.<o:p></o:p></span></p>
<p class="MsoNormal" style="text-align:justify"><span lang="EN-US">We offer excellent opportunities to pursue a career in or outside of academia.
<o:p></o:p></span></p>
<p class="MsoNormal" style="text-align:justify"><span lang="EN-US"><o:p> </o:p></span></p>
<p class="MsoNormal" style="margin-bottom:4.0pt;text-autospace:none"><b><span lang="EN-US"><o:p> </o:p></span></b></p>
<p class="MsoNormal" style="margin-bottom:7.5pt;line-height:15.75pt"><b><span lang="EN-US" style="font-size:13.5pt;font-family:Palatino;color:#0028A5;mso-fareast-language:DE">Place of work<o:p></o:p></span></b></p>
<p class="MsoNormal"><span lang="EN-US">Prof. Dr. Soeren Lienkamp Group of Remal Development and Reprogramming<br>
University of Zurich and ETH Zurich<br>
Institute of Anatomy<br>
Winterthurerstrasse 190 (Irchel Campus)<br>
CH-8057 Zurich<o:p></o:p></span></p>
<p class="MsoNormal" style="text-align:justify"><span lang="EN-US">Contact:<o:p></o:p></span></p>
<p class="MsoNormal" style="text-align:justify"><span lang="EN-US">Soeren Lienkamp,
<a href="mailto:soeren.lienkamp@anatomy.uzh.ch">soeren.lienkamp@anatomy.uzh.ch</a><o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US" style="font-size:12.0pt;font-family:"Times New Roman",serif;mso-fareast-language:DE"><o:p> </o:p></span></p>
<p class="MsoNormal" style="margin-bottom:7.5pt;line-height:15.75pt"><b><span lang="EN-US" style="font-size:13.5pt;font-family:Palatino;color:#0028A5;mso-fareast-language:DE">Start of employment<o:p></o:p></span></b></p>
<p class="MsoNormal" style="text-align:justify"><span lang="EN-US">By arrangement, ideally before August 1<sup>st</sup> 2025. Please
<a href="https://jobs.uzh.ch/job-vacancies/postdoctoral-researcher-in-biomedical-research/e31f8eef-0d6c-4527-aae4-f54ba2baf9f0">
submit your application here</a>, including a cover letter that highlights some past accomplishments (not necessary research related), CV, publication list and recommendation letters or contact details of at least one reference by June 15th 2025.<o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US" style="font-size:12.0pt;font-family:"Arial",sans-serif;color:black;mso-ligatures:none;mso-fareast-language:DE"><o:p> </o:p></span></p>
<p class="MsoNormal"><span lang="EN-US" style="font-family:"Arial",sans-serif;mso-ligatures:none;mso-fareast-language:DE"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none;mso-fareast-language:DE">-- <o:p></o:p></span></p>
</div>
<div>
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Arial",sans-serif;color:black;mso-ligatures:none;mso-fareast-language:DE"><br>
Prof. Soeren Lienkamp<br>
University of Zurich and ETH Zürich<br>
Institute of Anatomy<br>
Winterthurerstrasse 190<br>
CH-8057 Zurich<br>
Switzerland<br>
+41 (0) 44 635 53 48<br>
<br>
</span><span style="font-family:"Arial",sans-serif;mso-ligatures:none;mso-fareast-language:DE"><a href="mailto:soeren.lienkamp@uzh.ch"><span style="font-size:12.0pt;color:#0563C1">soeren.lienkamp@uzh.ch</span></a><o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Arial",sans-serif;mso-ligatures:none;mso-fareast-language:DE"><a href="http://www.lienkamplab.org"><span style="color:#0563C1">www.lienkamplab.org</span></a><o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Calibri",sans-serif;mso-ligatures:none;mso-fareast-language:DE"><o:p> </o:p></span></p>
<p class="MsoNormal"><span lang="EN-US" style="font-family:"Arial",sans-serif;color:black;mso-ligatures:none;mso-fareast-language:DE">----------<br>
You may receive emails from me outside of normal working hours. I do not expect a response from you outside of your own working pattern.<br>
----------</span><span lang="EN-US" style="font-family:"Arial",sans-serif;mso-ligatures:none;mso-fareast-language:DE"><o:p></o:p></span></p>
</div>
</div>
<p class="MsoNormal"><o:p> </o:p></p>
</div>
</body>
</html>