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<p>Dear Xenopus friends. We are looking for PhD students and
postdocs and if you know anyone interested, we would appreciate if
you could forward the information below to them. <br>
</p>
<p>Thanks a lot and all the best</p>
<p>Peter Walentek <br>
</p>
<p><font color="#ff0000"><br>
</font></p>
<p><font color="#ff0000"><b>LINK to job posting:
<a class="moz-txt-link-freetext" href="https://euraxess.ec.europa.eu/jobs/346670">https://euraxess.ec.europa.eu/jobs/346670</a></b></font></p>
<p><b>Text: <br>
</b></p>
<p>University Freiburg Medical Center is a leading institution in
biomedical research in the heart of Europe with close associations
to other institutions and centers in the tri-national Eucor area
(Germany, Switzerland and France). </p>
<p>The <strong>Walentek laboratory (Department of Medicine)</strong>
is located at the Institute for Disease Modeling and Targeted
Medicine (IMITATE) and <strong>is recruiting to fill multiple
positions for a 5 year ERC-funded project</strong> (MAGIX:
cordis.europa.eu/project/id/101170596) at the<strong> postdoctoral
level</strong>, however, <strong>candidates for PhD positions
are also encouraged to apply when they have relevant experience</strong>
in the areas listed below.<span> </span></p>
<p>We investigate how genomic, gene-regulatory and self-organizing
molecular mechanisms orchestrate tissue formation, function and
modification in development and disease. <span></span>We are using
an integrative and multi-level approach, and the laboratory
provides state-of-the-art research facilities for advanced light-
and electron microscopy, multi-omics approaches and
experimentation. This allows us to study airway-like mucociliary
epithelia in frogs and mice, and how their functions are modified
across organs and evolution to regulate microbiomes in health and
disease.<span> </span></p>
<p><strong>We are looking for highly motivated candidates who like
to work in an open and interdisciplinary environment to address
biomedical questions with novel approaches in the project areas
listed below. We encourage applications from qualified
candidates regardless of gender identity, disability,
nationality or any other demographic or personal factor. </strong><span><strong> </strong></span></p>
<ol>
<li><strong>Developmental and cell biology:</strong> Analysis of
Xenopus<span> </span>and mouse foregut development, cell types
and cilia function as well as testing the effects of signaling
pathways and transcription factors on tissue development and
cell type composition.</li>
</ol>
<p> </p>
<p><strong>Required skills and experience:</strong> The ideal
candidate holds a PhD in the areas of developmental or cell
biology, has experience in working with vertebrate models
(particularly mice), and has technical skills in imaging, genetic
modifications (genetic lines, CRISPR) and phenotype analyses. </p>
<p>Additional knowledge in computer-aided analyses (e.g. image
quantification) is beneficial. Potential applicants for a PhD
position need to demonstrate relevant experience in mouse genetics
and embryology or microbiome studies.</p>
<p> </p>
<ol start="2">
<li><strong>Bioinformatics and single-cell omics:</strong>
Collection, analysis and integration of temporally resolved
bulk- and single cell-RNA-seq/ATAC-seq datasets, assessment of
transcription factor binding and Histone modifications by
ChIP-seq and Cut&Run.</li>
</ol>
<p> </p>
<p><strong>Required skills and experience:</strong> The ideal
candidate holds a PhD in the areas of genetics and genomics or
bioinformatics, has experience (wet lab) in single cell
technologies as well as data analysis and multi-omics data
integration. Experience in addressing questions in developmental
biology as well as working with temporal-resolved datasets or
spatial-omics technologies is beneficial. Potential applicants for
a PhD position need to demonstrate relevant experience in
bioinformatics and omics data analysis, but are specifically
encouraged to apply.<span> </span></p>
<p> </p>
<ol start="3">
<li><strong>Mathematical modeling:</strong> Implement new data and
regulatory modules into an existing mathematical framework to
generate an in silico model of cell fate patterning mechanisms
and their modifications across organs.</li>
</ol>
<p> </p>
<p><strong>Required skills and experience:</strong> The ideal
candidate holds a MSc or PhD in mathematics, statistics or
biomedical sciences, has experience with modeling of biological
processes using ODE models based on experimental data, and is
interested in working at the intersection of systems biology and
theoretical modeling. Both PhD and postdoctoral candidates are
encouraged to apply. </p>
<p> </p>
<p><strong>We offer: </strong></p>
<p><strong>An excellent scientific environment</strong> and
state-of-the-art facilities, including opportunities for
scientific exchange and international exposure (e.g. through our
participation in the center of excellence CIBSS as well as
national research consortia SFB NephGen, FOR Cilia Dynamics or
HetCCI).</p>
<p><strong>Remuneration</strong> is based on the Collective
Agreement for the Public Sector of the Länder (TV-L 13+) <strong>including
all allowances customary in the public sector</strong>, e.g. end
of the year bonus, 30 days annual vacation, healthcare and pension
plans, job ticket for public transport, etc.</p>
<p><strong>Strong commitment to career development </strong>and
opportunities for additional internal and external mentoring,
training and career advancement programs, including graduate
schools (SGBM – University Freiburg, MOTIVATE – Medical Center
Freiburg, IMPRS – Max Planck Institute Freiburg). </p>
<p><strong>A collaborative dynamic team</strong> and a beautiful
city near the Black Forest with plenty of cultural sites and
outdoor activities close by.</p>
<p>Link to Walentek lab website: <a
href="https://www.uniklinik-freiburg.de/walentek-en.html"
class="ext moz-txt-link-freetext" data-extlink=""
target="_blank" rel="noopener noreferrer">https://www.uniklinik-freiburg.de/walentek-en.html</a></p>
<p> </p>
<p><strong>Application process: </strong></p>
<p>Please send</p>
<ol>
<li><strong>A motivation letter</strong> (max. 2 pages)
highlighting your background, relevant skills and your
motivation to apply for the position.</li>
<li>Academic <strong>CV, bibliography and contacts to 3
references</strong> familiar with your scientific work
(including previous MSc and PhD advisors).</li>
<li>A short description (max. ½ page) of <strong>your most
important scientific contribution</strong> (e.g. publication).</li>
</ol>
<p>Please send your application materials in from of <strong>a
single PDF</strong> to peter.walentek [at] uniklink-freiburg.de
<strong>until 31. August 2025</strong><strong>or earlier</strong>.
<strong>Earliest possible </strong><strong>start date: 01. August
2025</strong>. The application file name should contain your
last name and indicate the area 1.) “bio”, 2.) “omics”, 3.)
“math”. </p>
<p>In case of questions, please contact us. We are looking forward
to your application!</p>
<p></p>
<pre class="moz-signature" cols="72">--
Universitätsklinikum Freiburg
Innere Medizin IV & IMITATE - Institute for Disease Modeling and Targeted Medicine
Dr. Peter Walentek (He/Him)
Heisenberg Group Leader
Breisacher Str. 113 - 79106 Freiburg, Germany
Phone-Office: +49 761 270-63089
<a class="moz-txt-link-abbreviated" href="mailto:peter.walentek@medizin.uni-freiburg.de">peter.walentek@medizin.uni-freiburg.de</a>
<a class="moz-txt-link-abbreviated" href="http://www.uniklinik-freiburg.de/walentek-en.html">www.uniklinik-freiburg.de/walentek-en.html</a></pre>
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