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<p>Dear all, <br>
</p>
<p>we do have an exciting program ready for all interested to learn
about the basics of Xenopus experimentation as well as the latest
imaging and manipulation techniques. <br>
</p>
<p>Please encourage everyone interested to apply to the 2026 CSHL
Xenopus course bu January 16th. <br>
</p>
<p>We thank you all for supporting the course! </p>
<p>Rachel & Peter <br>
</p>
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<th valign="BASELINE" nowrap="nowrap" align="RIGHT">Subject:
</th>
<td>[EXTERN] Cell & Developmental Biology of Xenopus:
Gene Discovery & Disease - CSHL Course April 2026</td>
</tr>
<tr>
<th valign="BASELINE" nowrap="nowrap" align="RIGHT">Date: </th>
<td>Wed, 12 Nov 2025 09:02:52 -0500 (EST)</td>
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<th valign="BASELINE" nowrap="nowrap" align="RIGHT">From: </th>
<td>Cold Spring Harbor Laboratory Meetings & Courses
<a class="moz-txt-link-rfc2396E" href="mailto:meetmail-cshl.edu@shared1.ccsend.com"><meetmail-cshl.edu@shared1.ccsend.com></a></td>
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<th valign="BASELINE" nowrap="nowrap" align="RIGHT">Reply-To:
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<td><a class="moz-txt-link-abbreviated" href="mailto:meetmail@cshl.edu">meetmail@cshl.edu</a></td>
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<th valign="BASELINE" nowrap="nowrap" align="RIGHT">To: </th>
<td><a class="moz-txt-link-abbreviated" href="mailto:peter.walentek@medizin.uni-freiburg.de">peter.walentek@medizin.uni-freiburg.de</a></td>
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style="text-align: center; margin: 0;" align="center"><a
href="https://6zadfgnab.cc.rs6.net/tn.jsp?f=001gOQuNmqubhArtG0B1SY4SfavfORbSZPXs35wXAQWvpxvah2KSME8IdP8_RTT9cbE_Ar6nKjOybSQ783qv4qVDrMo-0Zr2ZEneDTRtxCCFacWYNKBp-cDP0rtQl-CpzhSQdJ9kPkdu4eJ-4sRVxzVQb4ckigeBzAT4JPpqfHMp5gzRnEs9LvqRVHnP1QQ-s0oO9ImQTYVsyw=&c=VIlzcouK90vAi-JJNHSZKTZuW3p-Izh5IVW_7iEMIJeAO-TyS3DdYA==&ch=fZ2nJwnWcHdaA6Lb30iqKxFCLrJ62a1p1LMuc9l40LA89OBTY-9khQ=="
rel="noopener noreferrer" target="_blank"
style="font-size: 27px; color: rgb(254, 243, 86); text-decoration: none; font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif; font-weight: bold; font-style: normal;"
moz-do-not-send="true">Cell & Developmental Biology of </a><a
href="https://6zadfgnab.cc.rs6.net/tn.jsp?f=001gOQuNmqubhArtG0B1SY4SfavfORbSZPXs35wXAQWvpxvah2KSME8IdP8_RTT9cbE_Ar6nKjOybSQ783qv4qVDrMo-0Zr2ZEneDTRtxCCFacWYNKBp-cDP0rtQl-CpzhSQdJ9kPkdu4eJ-4sRVxzVQb4ckigeBzAT4JPpqfHMp5gzRnEs9LvqRZct7bPGIQdLsct1XZWpF3A=&c=VIlzcouK90vAi-JJNHSZKTZuW3p-Izh5IVW_7iEMIJeAO-TyS3DdYA==&ch=fZ2nJwnWcHdaA6Lb30iqKxFCLrJ62a1p1LMuc9l40LA89OBTY-9khQ=="
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moz-do-not-send="true">Xenopus</a><a
href="https://6zadfgnab.cc.rs6.net/tn.jsp?f=001gOQuNmqubhArtG0B1SY4SfavfORbSZPXs35wXAQWvpxvah2KSME8IdP8_RTT9cbE_Ar6nKjOybSQ783qv4qVDrMo-0Zr2ZEneDTRtxCCFacWYNKBp-cDP0rtQl-CpzhSQdJ9kPkdu4eJ-4sRVxzVQb4ckigeBzAT4JPpqfHMp5gzRnEs9LvqRRW9CXlwATpAXg3NvnOybR8=&c=VIlzcouK90vAi-JJNHSZKTZuW3p-Izh5IVW_7iEMIJeAO-TyS3DdYA==&ch=fZ2nJwnWcHdaA6Lb30iqKxFCLrJ62a1p1LMuc9l40LA89OBTY-9khQ=="
rel="noopener noreferrer" target="_blank"
style="font-size: 27px; color: rgb(254, 243, 86); text-decoration: none; font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif; font-weight: bold; font-style: normal;"
moz-do-not-send="true">: Gene Discovery & Disease</a></p>
<p
style="text-align: center; margin: 0;" align="center"><span
style="font-size: 22px; color: rgb(255, 255, 255); font-weight: bold; font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif;">April
7 - 21, 2026</span></p>
<p
style="text-align: center; margin: 0;" align="center"><span
style="font-size: 22px; color: rgb(255, 255, 255); font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif;">Applications
Due: January 16,
2026</span></p>
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cellpadding="0" border="0">
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class="text_content-cell content-padding-horizontal"
style="text-align: center; font-family: Arial,Verdana,Helvetica,sans-serif; color: #717a80; font-size: 24px; line-height: 1.2; display: block; word-wrap: break-word; font-weight: bold; padding: 10px 20px;"
valign="top"
align="center">
<p
style="text-align: left; margin: 0;" align="left"><span
style="color: rgb(77, 133, 177); font-weight: bold;">Instructors</span></p>
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style="table-layout: fixed;"
width="100%" cellspacing="0"
cellpadding="0" border="0">
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<td
class="column column--1 scale stack" style="width: 100%;" valign="top"
align="center">
<table
class="text text--padding-vertical" style="table-layout: fixed;"
width="100%" cellspacing="0"
cellpadding="0" border="0">
<tbody>
<tr>
<td
class="text_content-cell content-padding-horizontal"
style="line-height: 1.5; text-align: left; font-family: Arial,Verdana,Helvetica,sans-serif; color: #403F42; font-size: 12px; display: block; word-wrap: break-word; padding: 10px 20px;"
valign="top"
align="left">
<p style="margin: 0;"><span
style="font-size: 16px; color: rgb(0, 57, 101); font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif; font-weight: bold;">Rachel
Miller, </span><span
style="font-size: 16px; color: rgb(0, 57, 101); font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif;">UTHealth
Houston, McGovern
Medical School</span></p>
<p style="margin: 0;"><span
style="font-size: 16px; color: rgb(0, 57, 101); font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif; font-weight: bold;">Peter
Walentek,</span><span
style="font-size: 16px; color: rgb(0, 57, 101); font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif;"> Universitätsklinikum
Freiburg, Germany</span></p>
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class="layout layout--heading layout--1-column"
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cellpadding="0" border="0">
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<tr>
<td
class="column column--1 scale stack" style="width: 100%;" valign="top"
align="center">
<table
class="text text--heading text--padding-vertical"
style="table-layout: fixed;"
width="100%" cellspacing="0"
cellpadding="0" border="0">
<tbody>
<tr>
<td
class="text_content-cell content-padding-horizontal"
style="text-align: center; font-family: Arial,Verdana,Helvetica,sans-serif; color: #717a80; font-size: 24px; line-height: 1.2; display: block; word-wrap: break-word; font-weight: bold; padding: 10px 20px;"
valign="top"
align="center">
<p
style="text-align: left; margin: 0;" align="left"><span
style="color: rgb(77, 133, 177); font-weight: bold;">Topics for 2026</span></p>
</td>
</tr>
</tbody>
</table>
</td>
</tr>
</tbody>
</table>
<table class="layout layout--1-column"
style="table-layout: fixed;"
width="100%" cellspacing="0"
cellpadding="0" border="0">
<tbody>
<tr>
<td
class="column column--1 scale stack" style="width: 100%;" valign="top"
align="center">
<table
class="text text--padding-vertical" style="table-layout: fixed;"
width="100%" cellspacing="0"
cellpadding="0" border="0">
<tbody>
<tr>
<td
class="text_content-cell content-padding-horizontal"
style="line-height: 1.5; text-align: left; font-family: Arial,Verdana,Helvetica,sans-serif; color: #403F42; font-size: 12px; display: block; word-wrap: break-word; padding: 10px 20px;"
valign="top"
align="left">
<p style="margin: 0;"><span
style="font-size: 18px; color: rgb(77, 133, 177); font-weight: bold; font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif; font-style: italic;">Gene
manipulation</span></p>
<ul
style="margin-top: 0; margin-bottom: 0;">
<li
style="font-size: 16px; color: rgb(0, 57, 101); font-weight: bold;"><span
style="font-size: 16px; color: rgb(0, 57, 101); font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif; font-weight: bold;">CRISPR/Cas9
knock-out</span></li>
<li
style="font-size: 16px; color: rgb(0, 57, 101); font-weight: bold;"><span
style="font-size: 16px; color: rgb(0, 57, 101); font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif; font-weight: bold;">Antisense
Morpholino
knock-down</span></li>
<li
style="font-size: 16px; color: rgb(0, 57, 101); font-weight: bold;"><span
style="font-size: 16px; color: rgb(0, 57, 101); font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif; font-weight: bold;">mRNA
and DNA
over-expression</span></li>
<li
style="font-size: 16px; color: rgb(0, 57, 101); font-weight: bold;"><span
style="font-size: 16px; color: rgb(0, 57, 101); font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif; font-weight: bold;">Small
molecule drug
treatment</span></li>
<li
style="font-size: 16px; color: rgb(0, 57, 101); font-weight: bold;"><span
style="font-size: 16px; color: rgb(0, 57, 101); font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif; font-weight: bold;">Transgenesis</span></li>
</ul>
<p style="margin: 0;"><br>
</p>
<p style="margin: 0;"><span
style="font-size: 18px; color: rgb(77, 133, 177); font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif; font-weight: bold; font-style: italic;">Experimental
Techniques</span></p>
<ul
style="margin-top: 0; margin-bottom: 0;">
<li
style="font-size: 16px; color: rgb(0, 57, 101); font-weight: bold;"><span
style="font-size: 16px; color: rgb(0, 57, 101); font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif; font-weight: bold;">Targeted
microinjections</span></li>
<li
style="font-size: 16px; color: rgb(0, 57, 101); font-weight: bold;"><span
style="font-size: 16px; color: rgb(0, 57, 101); font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif; font-weight: bold;">Tissue
transplantation</span></li>
<li
style="font-size: 16px; color: rgb(0, 57, 101); font-weight: bold;"><span
style="font-size: 16px; color: rgb(0, 57, 101); font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif; font-weight: bold;">Organoid
generation</span></li>
<li
style="font-size: 16px; color: rgb(0, 57, 101); font-weight: bold;">
<span
style="font-size: 16px; color: rgb(0, 57, 101); font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif; font-weight: bold;">Dissections
and </span><span
style="font-size: 16px; color: rgb(0, 57, 101); font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif; font-weight: bold; font-style: italic;">ex
vivo</span><span
style="font-size: 16px; color: rgb(0, 57, 101); font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif; font-weight: bold;">
organ culture</span>
</li>
<li
style="font-size: 16px; color: rgb(0, 57, 101); font-weight: bold;"><span
style="font-size: 16px; color: rgb(0, 57, 101); font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif; font-weight: bold;">Biomechanics</span></li>
<li
style="font-size: 16px; color: rgb(0, 57, 101); font-weight: bold;"><span
style="font-size: 16px; color: rgb(0, 57, 101); font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif; font-weight: bold;">Single
cell technologies</span></li>
</ul>
<p style="margin: 0;"><br>
</p>
<p style="margin: 0;"><span
style="font-size: 18px; color: rgb(77, 133, 177); font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif; font-weight: bold; font-style: italic;">Analysis
Methods</span></p>
<ul
style="margin-top: 0; margin-bottom: 0;">
<li
style="font-size: 16px; color: rgb(0, 57, 101); font-weight: bold;"><span
style="font-size: 16px; color: rgb(0, 57, 101); font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif; font-weight: bold;">Immuno-fluorescence
and labeling</span></li>
<li
style="font-size: 16px; color: rgb(0, 57, 101); font-weight: bold;">
<span
style="font-size: 16px; color: rgb(0, 57, 101); font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif; font-weight: bold;">mRNA</span><span
style="font-size: 16px; color: rgb(0, 57, 101); font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif; font-weight: bold; font-style: italic;">
in situ</span><span
style="font-size: 16px; color: rgb(0, 57, 101); font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif; font-weight: bold;">
hybridization and
hybridization
chain reaction
(HCR)</span>
</li>
<li
style="font-size: 16px; color: rgb(0, 57, 101); font-weight: bold;"><span
style="font-size: 16px; color: rgb(0, 57, 101); font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif; font-weight: bold;">Bioinformatics
and imaging
analysis</span></li>
<li
style="font-size: 16px; color: rgb(0, 57, 101); font-weight: bold;"><span
style="font-size: 16px; color: rgb(0, 57, 101); font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif; font-weight: bold;">High-resolution
confocal,
spinning-disc and
2-photon
microscopy</span></li>
<li
style="font-size: 16px; color: rgb(0, 57, 101); font-weight: bold;"><span
style="font-size: 16px; color: rgb(0, 57, 101); font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif; font-weight: bold;">Time-lapse
and live-cell
imaging</span></li>
<li
style="font-size: 16px; color: rgb(0, 57, 101); font-weight: bold;"><span
style="font-size: 16px; color: rgb(0, 57, 101); font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif; font-weight: bold;">Plate-based
imaging and
optical coherence
tomography</span></li>
</ul>
</td>
</tr>
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</table>
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</tr>
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style="color: rgb(77, 133, 177); font-weight: bold;">Invited Speakers</span></p>
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class="text_content-cell content-padding-horizontal"
style="line-height: 1.5; text-align: left; font-family: Arial,Verdana,Helvetica,sans-serif; color: #403F42; font-size: 12px; display: block; word-wrap: break-word; padding: 10px 20px;"
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align="left">
<p style="margin: 0;"><span
style="font-size: 16px; color: rgb(0, 57, 101); font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif; font-weight: bold;">Chenbei</span><span
style="font-size: 16px; color: rgb(0, 57, 101); font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif;"> </span><span
style="font-size: 16px; color: rgb(0, 57, 101); font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif; font-weight: bold;">Chang</span><span
style="font-size: 16px; color: rgb(0, 57, 101); font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif;">,
University of
Alabama at
Birmingham</span></p>
<p style="margin: 0;"><span
style="font-size: 16px; color: rgb(0, 57, 101); font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif; font-weight: bold;">Nicole</span><span
style="font-size: 16px; color: rgb(0, 57, 101); font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif;"> </span><span
style="font-size: 16px; color: rgb(0, 57, 101); font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif; font-weight: bold;">Edwards</span><span
style="font-size: 16px; color: rgb(0, 57, 101); font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif;">,
Cincinnati
Children's Hospital</span></p>
<p style="margin: 0;"><span
style="font-size: 16px; color: rgb(0, 57, 101); font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif; font-weight: bold;">Kerstin</span><span
style="font-size: 16px; color: rgb(0, 57, 101); font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif;"> </span><span
style="font-size: 16px; color: rgb(0, 57, 101); font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif; font-weight: bold;">Feistel</span><span
style="font-size: 16px; color: rgb(0, 57, 101); font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif;">,
University of
Hohenheim, Germany </span></p>
<p style="margin: 0;"><span
style="font-size: 16px; color: rgb(0, 57, 101); font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif; font-weight: bold;">Douglas</span><span
style="font-size: 16px; color: rgb(0, 57, 101); font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif;"> </span><span
style="font-size: 16px; color: rgb(0, 57, 101); font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif; font-weight: bold;">Houston</span><span
style="font-size: 16px; color: rgb(0, 57, 101); font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif;">,
The University of
Iowa</span></p>
<p style="margin: 0;"><span
style="font-size: 16px; color: rgb(0, 57, 101); font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif; font-weight: bold;">Soeren</span><span
style="font-size: 16px; color: rgb(0, 57, 101); font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif;"> </span><span
style="font-size: 16px; color: rgb(0, 57, 101); font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif; font-weight: bold;">Lienkamp</span><span
style="font-size: 16px; color: rgb(0, 57, 101); font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif;">,
University of
Zurich, Switzerland </span></p>
<p style="margin: 0;"><span
style="font-size: 16px; color: rgb(0, 57, 101); font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif; font-weight: bold;">Roberto</span><span
style="font-size: 16px; color: rgb(0, 57, 101); font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif;"> </span><span
style="font-size: 16px; color: rgb(0, 57, 101); font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif; font-weight: bold;">Mayor</span><span
style="font-size: 16px; color: rgb(0, 57, 101); font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif;">,
University College
London, UK</span></p>
<p style="margin: 0;"><span
style="font-size: 16px; color: rgb(0, 57, 101); font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif; font-weight: bold;">Jacques</span><span
style="font-size: 16px; color: rgb(0, 57, 101); font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif;"> </span><span
style="font-size: 16px; color: rgb(0, 57, 101); font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif; font-weight: bold;">Robert</span><span
style="font-size: 16px; color: rgb(0, 57, 101); font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif;">,
University of
Rochester Medical
Center</span></p>
<p style="margin: 0;"><span
style="font-size: 16px; color: rgb(0, 57, 101); font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif; font-weight: bold;">Jakub</span><span
style="font-size: 16px; color: rgb(0, 57, 101); font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif;"> </span><span
style="font-size: 16px; color: rgb(0, 57, 101); font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif; font-weight: bold;">Sedzinski</span><span
style="font-size: 16px; color: rgb(0, 57, 101); font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif;">,
University of
Copenhagen, Denmark</span></p>
<p style="margin: 0;"><span
style="font-size: 16px; color: rgb(0, 57, 101); font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif; font-weight: bold;">Kelly</span><span
style="font-size: 16px; color: rgb(0, 57, 101); font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif;"> </span><span
style="font-size: 16px; color: rgb(0, 57, 101); font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif; font-weight: bold;">Tseng</span><span
style="font-size: 16px; color: rgb(0, 57, 101); font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif;">,
University of
Nevada, Las Vegas</span></p>
<p style="margin: 0;"><span
style="font-size: 16px; color: rgb(0, 57, 101); font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif; font-weight: bold;">Coral</span><span
style="font-size: 16px; color: rgb(0, 57, 101); font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif;"> </span><span
style="font-size: 16px; color: rgb(0, 57, 101); font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif; font-weight: bold;">Zhou</span><span
style="font-size: 16px; color: rgb(0, 57, 101); font-family: Century Gothic, Calibri, Helvetica, Arial, sans-serif;">,
University of Kansas</span></p>
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