[Xenopus] Myotropic viral vectors for adult Xenopus

Godavarthi, Swetha K skgodavarthi at pitt.edu
Tue Nov 26 13:36:55 EST 2024


Hello all,
I am interested in targeted gene delivery to adult Xenopus muscles. I am looking for viral vectors to accomplish this. The rVSV-G that has been shown to work in adult Xenopus neurons unfortunately appears to have poor myotropism (https://pubmed.ncbi.nlm.nih.gov/30416430/). I came across another study using rabies virus but in Xenopus tadpoles. Has anybody successfully used either rVSV-G or any other viral vector for adult Xenopus that is also myotropic?

Thanks in advance for your inputs!

Best,
Swetha
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