[Xenopus] Multiple Postdoc and PhD positions in developmental biology, genetics, bioinformatics and mathematical modeling - Walentek Lab - Freiburg, Germany

[Dr. Peter Walentek]

Dear Xenopus friends. We are looking for PhD students and postdocs and 
if you know anyone interested, we would appreciate if you could forward 
the information below to them.

Thanks a lot and all the best

Peter Walentek


*LINK to job posting: https://euraxess.ec.europa.eu/jobs/346670*

*Text:
*

University Freiburg Medical Center is a leading institution in 
biomedical research in the heart of Europe with close associations to 
other institutions and centers in the tri-national Eucor area (Germany, 
Switzerland and France).

The *Walentek laboratory (Department of Medicine)* is located at the 
Institute for Disease Modeling and Targeted Medicine (IMITATE) and *is 
recruiting to fill multiple positions for a 5 year ERC-funded project* 
(MAGIX: cordis.europa.eu/project/id/101170596) at the*postdoctoral 
level*, however, *candidates for PhD positions are also encouraged to 
apply when they have relevant experience* in the areas listed below.

We investigate how genomic, gene-regulatory and self-organizing 
molecular mechanisms orchestrate tissue formation, function and 
modification in development and disease. We are using an integrative and 
multi-level approach, and the laboratory provides state-of-the-art 
research facilities for advanced light- and electron microscopy, 
multi-omics approaches and experimentation. This allows us to study 
airway-like mucociliary epithelia in frogs and mice, and how their 
functions are modified across organs and evolution to regulate 
microbiomes in health and disease.

*We are looking for highly motivated candidates who like to work in an 
open and interdisciplinary environment to address biomedical questions 
with novel approaches in the project areas listed below. We encourage 
applications from qualified candidates regardless of gender identity, 
disability, nationality or any other demographic or personal factor. ***

 1. *Developmental and cell biology:* Analysis of Xenopusand mouse
    foregut development, cell types and cilia function as well as
    testing the effects of signaling pathways and transcription factors
    on tissue development and cell type composition.

*Required skills and experience:* The ideal candidate holds a PhD in the 
areas of developmental or cell biology, has experience in working with 
vertebrate models (particularly mice), and has technical skills in 
imaging, genetic modifications (genetic lines, CRISPR) and phenotype 
analyses.

Additional knowledge in computer-aided analyses (e.g. image 
quantification) is beneficial. Potential applicants for a PhD position 
need to demonstrate relevant experience in mouse genetics and embryology 
or microbiome studies.

 2. *Bioinformatics and single-cell omics:* Collection, analysis and
    integration of temporally resolved bulk- and single
    cell-RNA-seq/ATAC-seq datasets, assessment of transcription factor
    binding and Histone modifications by ChIP-seq and Cut&Run.

*Required skills and experience:* The ideal candidate holds a PhD in the 
areas of genetics and genomics or bioinformatics, has experience (wet 
lab) in single cell technologies as well as data analysis and 
multi-omics data integration. Experience in addressing questions in 
developmental biology as well as working with temporal-resolved datasets 
or spatial-omics technologies is beneficial. Potential applicants for a 
PhD position need to demonstrate relevant experience in bioinformatics 
and omics data analysis, but are specifically encouraged to apply.

 3. *Mathematical modeling:* Implement new data and regulatory modules
    into an existing mathematical framework to generate an in silico
    model of cell fate patterning mechanisms and their modifications
    across organs.

*Required skills and experience:* The ideal candidate holds a MSc or PhD 
in mathematics, statistics or biomedical sciences, has experience with 
modeling of biological processes using ODE models based on experimental 
data, and is interested in working at the intersection of systems 
biology and theoretical modeling. Both PhD and postdoctoral candidates 
are encouraged to apply.

*We offer: *

*An excellent scientific environment* and state-of-the-art facilities, 
including opportunities for scientific exchange and international 
exposure (e.g. through our participation in the center of excellence 
CIBSS as well as national research consortia SFB NephGen, FOR Cilia 
Dynamics or HetCCI).

*Remuneration* is based on the Collective Agreement for the Public 
Sector of the Länder (TV-L 13+) *including all allowances customary in 
the public sector*, e.g. end of the year bonus, 30 days annual vacation, 
healthcare and pension plans, job ticket for public transport, etc.

*Strong commitment to career development *and opportunities for 
additional internal and external mentoring, training and career 
advancement programs, including graduate schools (SGBM – University 
Freiburg, MOTIVATE – Medical Center Freiburg, IMPRS – Max Planck 
Institute Freiburg).

*A collaborative dynamic team* and a beautiful city near the Black 
Forest with plenty of cultural sites and outdoor activities close by.

Link to Walentek lab website: 
https://www.uniklinik-freiburg.de/walentek-en.html 
<https://www.uniklinik-freiburg.de/walentek-en.html>

*Application process: *

Please send

 1. *A motivation letter* (max. 2 pages) highlighting your background,
    relevant skills and your motivation to apply for the position.
 2. Academic *CV, bibliography and contacts to 3 references* familiar
    with your scientific work (including previous MSc and PhD advisors).
 3. A short description (max. ½ page) of *your most important scientific
    contribution* (e.g. publication).

Please send your application materials in from of *a single PDF* to 
peter.walentek [at] uniklink-freiburg.de *until 31. August 2025**or 
earlier*. *Earliest possible **start date: 01. August 2025*. The 
application file name should contain your last name and indicate the 
area 1.) “bio”, 2.) “omics”, 3.) “math”.

In case of questions, please contact us. We are looking forward to your 
application!

-- 
Universitätsklinikum Freiburg
Innere Medizin IV & IMITATE - Institute for Disease Modeling and Targeted Medicine

Dr. Peter Walentek (He/Him)
Heisenberg Group Leader

Breisacher Str. 113 - 79106 Freiburg, Germany
Phone-Office: +49 761 270-63089

peter.walentek at medizin.uni-freiburg.de
www.uniklinik-freiburg.de/walentek-en.html
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